PTS purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PTS protein.
Immunogen
PTS (NP_000308.1, 1 a.a. ~ 145 a.a) full-length human protein.
Sequence
MSTEGGGRRCQAQVSRRISFSASHRLYSKFLSDEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNLADLKKYMEEAIMQPLDHKNLDMDVPYFADVVSTTENVAVYIWDNLQKVLPVGVLYKVKVYETDNNIVVYKGE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (88)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PTS expression in transfected 293T cell line (H00005805-T01) by PTS MaxPab polyclonal antibody.
Lane 1: PTS transfected lysate(15.95 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PTS on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — PTS
Entrez GeneID
5805GeneBank Accession#
NM_000317.1Protein Accession#
NP_000308.1Gene Name
PTS
Gene Alias
FLJ97081, PTPS
Gene Description
6-pyruvoyltetrahydropterin synthase
Omim ID
261640Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq
Other Designations
6-pyruvoyl tetrahydrobiopterin synthase|6-pyruvoyl-tetrahydropterin synthase|PTP synthase
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