PTS 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PTS full-length
Host
Human
Theoretical MW (kDa)
16.06
Interspecies Antigen Sequence
Mouse (87); Rat (88)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PTS antibody (H00005805-B01) by Western Blots.
SDS-PAGE Gel
PTS transfected lysate.
Western Blot
Lane 1: PTS transfected lysate ( 16.06 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PTS
Entrez GeneID
5805GeneBank Accession#
NM_000317.1Protein Accession#
NP_000308.1Gene Name
PTS
Gene Alias
FLJ97081, PTPS
Gene Description
6-pyruvoyltetrahydropterin synthase
Omim ID
261640Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq
Other Designations
6-pyruvoyl tetrahydrobiopterin synthase|6-pyruvoyl-tetrahydropterin synthase|PTP synthase
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Interactome
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Pathway
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Disease
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