PSMD10 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PSMD10 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PSMD10 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PSMD10 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PSMD10
Entrez GeneID
5716GeneBank Accession#
PSMD10Gene Name
PSMD10
Gene Alias
dJ889N15.2, p28
Gene Description
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
Omim ID
603480Gene Ontology
HyperlinkGene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20. [provided by RefSeq
Other Designations
26S proteasome non-ATPase regulatory subunit 10|26S proteasome regulatory subunit p28|OTTHUMP00000023827|OTTHUMP00000023828|ankyrin repeat protein|gankyrin|hepatocellular carcinoma-associated protein p28-II|proteasome 26S non-ATPase subunit 10
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Interactome
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+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
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