MX2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human MX2 partial ORF ( NP_002454.1, 521 a.a. - 620 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
QKAMEIIQQAFINVAKKHFGEFFNLNQTVQSTIEDIKVKHTAKAENMIQLQFRMEQMVFCQDQIYSVVLKKVREEIFNPLGTPSQNMKLNSHFPSNESSV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MX2
Entrez GeneID
4600GeneBank Accession#
NM_002463Protein Accession#
NP_002454.1Gene Name
MX2
Gene Alias
MXB
Gene Description
myxovirus (influenza virus) resistance 2 (mouse)
Omim ID
147890Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq
Other Designations
interferon-regulated resistance GTP-binding protein MXB|myxovirus resistance protein 2|second interferon-induced protein p78
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Interactome
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Disease
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