LOXL1 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human LOXL1 protein.
Immunogen
LOXL1 (NP_005567.2, 1 a.a. ~ 574 a.a) full-length human protein.
Sequence
MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (84)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of LOXL1 expression in transfected 293T cell line (H00004016-T01) by LOXL1 MaxPab polyclonal antibody.
Lane 1: LOXL1 transfected lysate(63.10 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of LOXL1 transfected lysate using anti-LOXL1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with LOXL1 purified MaxPab mouse polyclonal antibody (B01P) (H00004016-B01P).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to LOXL1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — LOXL1
Entrez GeneID
4016GeneBank Accession#
NM_005576.2Protein Accession#
NP_005567.2Gene Name
LOXL1
Gene Alias
LOL, LOXL
Gene Description
lysyl oxidase-like 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq
Other Designations
lysyl oxidase homolog 1
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Interactome
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Disease
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