KPNA4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human KPNA4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human KPNA4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human KPNA4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — KPNA4
Entrez GeneID
3840GeneBank Accession#
KPNA4Gene Name
KPNA4
Gene Alias
IPOA3, MGC12217, MGC26703, QIP1, SRP3
Gene Description
karyopherin alpha 4 (importin alpha 3)
Omim ID
602970Gene Ontology
HyperlinkGene Summary
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq
Other Designations
importin alpha 3|importin-alpha-Q1|karyopherin alpha 4
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Interactome
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