ING1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
ING1 transfected lysate.
Western Blot
Lane 1: ING1 transfected lysate ( 11.11 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ING1 full-length
Host
Human
Theoretical MW (kDa)
30.8
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ING1 antibody (H00003621-B01) by Western Blots.
SDS-PAGE Gel
ING1 transfected lysate.
Western Blot
Lane 1: ING1 transfected lysate ( 11.11 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ING1
Entrez GeneID
3621GeneBank Accession#
NM_198219Protein Accession#
NP_937862Gene Name
ING1
Gene Alias
p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
Gene Description
inhibitor of growth family, member 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000018703|OTTHUMP00000018704|OTTHUMP00000018705|OTTHUMP00000018706|growth inhibitor ING1|growth inhibitory protein ING1|inhibitor of growth 1|tumor suppressor ING1
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Interactome
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Disease
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