HGD purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human HGD protein.
Immunogen
HGD (AAH71757.1, 1 a.a. ~ 445 a.a) full-length human protein.
Sequence
MAELKYISGFGNECSSEDPRCPGSLPEGQNNPQVCPYNLYAEQLSGSAFTCPRSTNKRSWLYRILPSVSHKPFESIDEGHVTHNWDEVDPDPNQLRWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFLIVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLKSHFTPNSRNPAEPN
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HGD expression in transfected 293T cell line (H00003081-T01) by HGD MaxPab polyclonal antibody.
Lane 1: HGD transfected lysate(50.00 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — HGD
Entrez GeneID
3081GeneBank Accession#
NM_000187.1Protein Accession#
AAH71757.1Gene Name
HGD
Gene Alias
AKU, HGO
Gene Description
homogentisate 1,2-dioxygenase (homogentisate oxidase)
Gene Ontology
HyperlinkGene Summary
Homogentisate 1,2-dioxygenase (HGD) gene mutations are the molecular cause of alkaptonuria, a rare hereditary disorder of the phenylalanine catabolism. The highest expression of HGD is in the prostate, small intestine, colon, and liver. The HGD gene contains 14 exons. Conflicting reports have placed the gene at 3q2, 3q13.3-q21, 3q21-q24, 3q21-q23, or 3q25-q26. [provided by RefSeq
Other Designations
homogentisate 1,2-dioxygenase|homogentisicase
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Interactome
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Pathway
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Publication Reference
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Adaptation of phenylalanine and tyrosine catabolic pathway to hibernation in bats.
Pan YH, Zhang Y, Cui J, Liu Y, McAllan BM, Liao CC, Zhang S.
PLoS One 2013 Apr; 8(4):e62039.
Application:WB, Bat, Pig, Mouse, Rat, Liver.
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Adaptation of phenylalanine and tyrosine catabolic pathway to hibernation in bats.
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