E2F2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of E2F2 expression in transfected 293T cell line (H00001870-T01) by E2F2 MaxPab polyclonal antibody.
Lane 1: E2F2 transfected lysate(9.24 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human E2F2 protein.
Immunogen
E2F2 (AAH07609, 1 a.a. ~ 83 a.a) full-length human protein.
Sequence
MESRSVAQAGVQWPDLGSLQPLPPRFKRFFCLSLQSSWDYRHAPPRPANFVFLVETGFCHVSQAGLELLTSSDPPPRPPKVLR
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of E2F2 expression in transfected 293T cell line (H00001870-T01) by E2F2 MaxPab polyclonal antibody.
Lane 1: E2F2 transfected lysate(9.24 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — E2F2
Entrez GeneID
1870GeneBank Accession#
BC007609Protein Accession#
AAH07609Gene Name
E2F2
Gene Alias
E2F-2
Gene Description
E2F transcription factor 2
Omim ID
600426Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq
Other Designations
OTTHUMP00000003257
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Interactome
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