DLX3 monoclonal antibody (M02), clone 3B8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant DLX3.
Immunogen
DLX3 (AAH12361, 1 a.a. ~ 287 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (57.31 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
DLX3 monoclonal antibody (M02), clone 3B8 Western Blot analysis of DLX3 expression in A-549 ( Cat # L025V1 ).Western Blot (Transfected lysate)
Western Blot analysis of DLX3 expression in transfected 293T cell line by DLX3 monoclonal antibody (M02), clone 3B8.
Lane 1: DLX3 transfected lysate(31.7 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DLX3 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — DLX3
Entrez GeneID
1747GeneBank Accession#
BC012361Protein Accession#
AAH12361Gene Name
DLX3
Gene Alias
AI4, TDO
Gene Description
distal-less homeobox 3
Gene Ontology
HyperlinkGene Summary
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism. [provided by RefSeq
Other Designations
distal-less homeo box 3
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Interactome
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Disease
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Publication Reference
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NOTCH1 signaling regulates the BMP2/DLX-3 directed osteogenic differentiation of dental follicle cells.
Viale-Bouroncle S, Gosau M, Morsczeck C.
Biochemical and Biophysical Research Communications 2014 Jan; 443(2):500.
Application:WB, Human, Dental follicle cells.
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NOTCH1 signaling regulates the BMP2/DLX-3 directed osteogenic differentiation of dental follicle cells.
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