CBFA2T3 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CBFA2T3 full-length
Host
Human
Theoretical MW (kDa)
67.76
Interspecies Antigen Sequence
Mouse (81); Rat (81)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CBFA2T3 antibody (H00000863-B01) by Western Blots.
SDS-PAGE Gel
CBFA2T3 transfected lysate.
Western Blot
Lane 1: CBFA2T3 transfected lysate ( 67.76 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CBFA2T3
Entrez GeneID
863GeneBank Accession#
BC062624.1Protein Accession#
AAH62624.1Gene Name
CBFA2T3
Gene Alias
ETO2, MTG16, MTGR2, ZMYND4
Gene Description
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Omim ID
603870Gene Ontology
HyperlinkGene Summary
The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of this gene. In addition, this gene is a putative breast tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene, and a brefeldin A-sensitive association of RII-alpha protein with one of the isoforms has been demonstrated in the Golgi apparatus. [provided by RefSeq
Other Designations
MTG8-related gene 2|myeloid translocation gene on chromosome 16|zinc finger MYND domain-containing protein 4
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