CASQ2 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CASQ2 full-length
Host
Human
Theoretical MW (kDa)
44
Interspecies Antigen Sequence
Mouse (91); Rat (92)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CASQ2 antibody (H00000845-B01) by Western Blots.
SDS-PAGE Gel
CASQ2 transfected lysate.
Western Blot
Lane 1: CASQ2 transfected lysate ( 44 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CASQ2
Entrez GeneID
845GeneBank Accession#
BC022288.1Protein Accession#
NP_001223.2Gene Name
CASQ2
Gene Alias
FLJ26321, FLJ93514, PDIB2
Gene Description
calsequestrin 2 (cardiac muscle)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq
Other Designations
OTTHUMP00000013749|calsequestrin 2, fast-twitch, cardiac muscle|cardiac calsequestrin 2
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