BGN 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BGN full-length
Host
Human
Theoretical MW (kDa)
41.7
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BGN antibody (H00000633-D01P) by Western Blots.
SDS-PAGE Gel
BGN transfected lysate.
Western Blot
Lane 1: BGN transfected lysate ( 41.70 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — BGN
Entrez GeneID
633GeneBank Accession#
NM_001711.3Protein Accession#
NP_001702.1Gene Name
BGN
Gene Alias
DSPG1, PG-S1, PGI, SLRR1A
Gene Description
biglycan
Omim ID
301870Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta. It may promote neuronal survival. This gene is a candidate gene for the Happle syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000025928|biglycan proteoglycan|bone/cartilage proteoglycan-I|dermatan sulphate proteoglycan I|small leucine-rich protein 1A
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