ATIC purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Tissue lysate)
ATIC MaxPab polyclonal antibody. Western Blot analysis of ATIC expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of ATIC expression in transfected 293T cell line (H00000471-T01) by ATIC MaxPab polyclonal antibody.
Lane 1: ATIC transfected lysate(65.12 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ATIC protein.
Immunogen
ATIC (NP_004035.2, 1 a.a. ~ 592 a.a) full-length human protein.
Sequence
MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ATIC MaxPab polyclonal antibody. Western Blot analysis of ATIC expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of ATIC expression in transfected 293T cell line (H00000471-T01) by ATIC MaxPab polyclonal antibody.
Lane 1: ATIC transfected lysate(65.12 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ATIC
Entrez GeneID
471GeneBank Accession#
NM_004044.4Protein Accession#
NP_004035.2Gene Name
ATIC
Gene Alias
AICAR, AICARFT, FLJ93545, IMPCHASE, PURH
Gene Description
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Gene Ontology
HyperlinkGene Summary
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq
Other Designations
AICARFT/IMPCHASE
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Interactome
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Pathway
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Disease
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