MALT1 Split FISH Probe
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Specification
Product Description
Labeled FISH probes for identification of gene split using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: MALT1
Size: Approximately 410kb
Fluorophore: Texas Red
Location: 18q21.32Probe 2
Name: MALT1
Size: Approximately 650Kb
Fluorophore: FITC
Location: 18q21.32Origin
Human
Source
Genomic DNA
Reactivity
Human
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulatory Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome.
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — MALT1
Entrez GeneID
10892Gene Name
MALT1
Gene Alias
DKFZp434L132, MLT, MLT1
Gene Description
mucosa associated lymphoid tissue lymphoma translocation gene 1
Omim ID
604860Gene Ontology
HyperlinkGene Summary
This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
MALT associated translocation|MALT-lymphoma associated translocation|caspase-like protein|mucosa associated lymphoid tissue lymphoma translocation protein 1|paracaspase
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Interactome
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Pathway
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Disease
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