GH1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GH1.
Immunogen
A synthetic peptide corresponding to amino acids 172-192 of human GH1.
Sequence
DKVETFLRIVQCRSVEGSCGF
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:50000)
Dot Blot (1:50000)
Immunohistochemistry (1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
Dot Blot
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Gene Info — GH1
Entrez GeneID
2688Gene Name
GH1
Gene Alias
GH, GH-N, GHN, hGH-N
Gene Description
growth hormone 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq
Other Designations
pituitary growth hormone
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Interactome
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Pathway
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Disease
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Publication Reference
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Spontaneous oscillations of intracellular calcium and growth hormone secretion.
Holl RW, Thorner MO, Mandell GL, Sullivan JA, Sinha YN, Leong DA.
The Journal of Biological Chemistry 1988 Jul; 263(20):9682.
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Spontaneous oscillations of intracellular calcium and growth hormone secretion.
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