PDCD1 monoclonal antibody (M21), clone 5F5
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant PDCD1.
Immunogen
PDCD1 (AAH74740.1, 22 a.a. ~ 170 a.a) partial recombinant protein.
Sequence
GWFLDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTERRAEVPTAHPSPSPRPAGQFQTLV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (62); Rat (67)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (18.59 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PDCD1 monoclonal antibody (M21), clone 5F5. Western Blot analysis of PDCD1 expression in mouse heart.Western Blot (Cell lysate)
PDCD1 monoclonal antibody (M21), clone 5F5. Western Blot analysis of PDCD1 expression in Jurkat.Western Blot (Cell lysate)
PDCD1 monoclonal antibody (M21), clone 5F5. Western Blot analysis of PDCD1 expression in Raji.Western Blot (Cell lysate)
PDCD1 monoclonal antibody (M21), clone 5F5. Western Blot analysis of PDCD1 expression in NIH/3T3.Western Blot (Cell lysate)
PDCD1 monoclonal antibody (M21), clone 5F5. Western Blot analysis of PDCD1 expression in MOLT4.Western Blot (Recombinant protein)
ELISA
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Gene Info — PDCD1
Entrez GeneID
5133GeneBank Accession#
BC074740.2Protein Accession#
AAH74740.1Gene Name
PDCD1
Gene Alias
CD279, PD1, SLEB2, hPD-1, hPD-l
Gene Description
programmed cell death 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
Other Designations
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Interactomes
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Pathways
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Diseases
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