CA11 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human CA11 protein.
Immunogen
CA11 (NP_001208.2, 1 a.a. ~ 328 a.a) full-length human protein.
Sequence
MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGVPHGR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CA11 expression in transfected 293T cell line (H00000770-T04) by CA11 MaxPab polyclonal antibody.
Lane 1: CA11 transfected lysate(36.08 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CA11
Entrez GeneID
770GeneBank Accession#
NM_001217.3Protein Accession#
NP_001208.2Gene Name
CA11
Gene Alias
CARP2, CARPX1
Gene Description
carbonic anhydrase XI
Omim ID
604644Gene Ontology
HyperlinkGene Summary
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq
Other Designations
carbonic anhydrase-related protein 2|carbonic anhydrase-related protein XI
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