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Last updated: 2014/11/23
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GDNF polyclonal antibody

  • Catalog # : PAB14339
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  • Specification
  • Product Description:
  • Sheep polyclonal antibody raised against recombinant GDNF.
  • Immunogen:
  • Recombinant protein corresponding to human GDNF.
  • Host:
  • Sheep
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • No cross reactivity with NTN has been observed in western blot analysis.
  • Form:
  • Lyophilized
  • Recommend Usage:
  • Immunohistochemistry (1 ug/mL)
    Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical staining of Glial Derived Neurotrophic Factor (GDNF) in rat dorsal root ganglia using GDNF polyclonal antibody (Cat # PAB14339).
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 2668
  • Gene Name:
  • GDNF
  • Gene Alias:
  • ATF1,ATF2,HFB1-GDNF
  • Gene Description:
  • glial cell derived neurotrophic factor
  • Gene Summary:
  • This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq
  • Other Designations:
  • astrocyte-derived trophic factor,glial cell line derived neurotrophic factor,glial derived neurotrophic factor
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