GDNF recombinant monoclonal antibody, clone R01-1H1
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human GDNF.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human GDNF.
Theoretical MW (kDa)
Calculated MW: 24 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end use.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol and 0.02% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Flow Cytometry
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Gene Info — GDNF
Entrez GeneID
2668Gene Name
GDNF
Gene Alias
ATF1, ATF2, HFB1-GDNF
Gene Description
glial cell derived neurotrophic factor
Gene Ontology
HyperlinkGene Summary
This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq
Other Designations
astrocyte-derived trophic factor|glial cell line derived neurotrophic factor|glial derived neurotrophic factor
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Interactome
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Disease
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