CLDN1 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human CLDN1 protein.
Immunogen
CLDN1 (NP_066924.1, 1 a.a. ~ 211 a.a) full-length human protein.
Sequence
MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (90)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CLDN1 expression in transfected 293T cell line (H00009076-T02) by CLDN1 MaxPab polyclonal antibody.
Lane 1: CLDN1 transfected lysate(22.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of CLDN1 transfected lysate using anti-CLDN1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CLDN1 MaxPab mouse polyclonal antibody (B01) (H00009076-B01). -
Gene Info — CLDN1
Entrez GeneID
9076GeneBank Accession#
NM_021101.3Protein Accession#
NP_066924.1Gene Name
CLDN1
Gene Alias
CLD1, ILVASC, SEMP1
Gene Description
claudin 1
Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq
Other Designations
senescence-associated epithelial membrane protein 1
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Interactomes
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Pathways
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Diseases
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