HNRNPK purified MaxPab mouse polyclonal antibody (B02P)
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More Files
- More Functions
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human HNRNPK protein.
Immunogen
HNRNPK (NP_112552.1, 1 a.a. ~ 463 a.a) full-length human protein.
Sequence
METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HNRNPK expression in transfected 293T cell line (H00003190-T02) by HNRNPK MaxPab polyclonal antibody.
Lane 1: HNRPK transfected lysate(51.00 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to HNRPK on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — HNRNPK
Entrez GeneID
3190GeneBank Accession#
NM_031262.1Protein Accession#
NP_112552.1Gene Name
HNRNPK
Gene Alias
CSBP, FLJ41122, HNRPK, TUNP
Gene Description
heterogeneous nuclear ribonucleoprotein K
Omim ID
600712Gene Ontology
HyperlinkGene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq
Other Designations
OTTHUMP00000021554|OTTHUMP00000021557|OTTHUMP00000021558|dC-stretch binding protein|transformation upregulated nuclear protein
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Interactomes
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Publication Reference
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Heterogeneous nuclear ribonucleoprotein k interacts with abi-1 at postsynaptic sites and modulates dendritic spine morphology.
Proepper C, Steinestel K, Schmeisser MJ, Heinrich J, Steinestel J, Bockmann J, Liebau S, Boeckers TM.
PLoS One 2011 Nov; 6(11):e27045.
Application:IP, Rat, Brain.
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Heterogeneous nuclear ribonucleoprotein k interacts with abi-1 at postsynaptic sites and modulates dendritic spine morphology.
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