PARP4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PARP4.
Immunogen
A synthetic peptide corresponding to human PARP4.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is specific to PARP4.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50~1:100)
IELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using PARP4 polyclonal antibody (Cat # PAB18062).
Peptide "+" means "with peptide blocking".Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — PARP4
Entrez GeneID
143Protein Accession#
Q9UKK3Gene Name
PARP4
Gene Alias
ADPRTL1, PARPL, PH5P, VAULT3, VPARP, VWA5C, p193
Gene Description
poly (ADP-ribose) polymerase family, member 4
Omim ID
607519Gene Ontology
HyperlinkGene Summary
This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq
Other Designations
ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1|H5 proline-rich|I-alpha-I-related|OTTHUMP00000018130|OTTHUMP00000042288|PARP-related|poly(ADP-ribose) synthetase|poly(ADP-ribosyl)transferase-like 1|vault protein, 193-kDa|von Willebrand f
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Interactome
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Pathway
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Disease
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Publication Reference
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The DNA sequence and analysis of human chromosome 13.
Dunham A, Matthews LH, Burton J, Ashurst JL, Howe KL, Ashcroft KJ, Beare DM, Burford DC, Hunt SE, Griffiths-Jones S, Jones MC, Keenan SJ, Oliver K, Scott CE, Ainscough R, Almeida JP, Ambrose KD, Andrews DT, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Bannerjee R, Barlow KF, Bates K, Beasley H, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burrill W, Carder C, Carter NP, Chapman JC, Clamp ME, Clark SY, Clarke G, Clee CM, Clegg SC, Cobley V, Collins JE, Corby N, Coville GJ, Deloukas P, Dhami P, Du
Nature 2004 Apr; 428(6982):522.
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Identification of a novel gene (ADPRTL1) encoding a potential Poly(ADP-ribosyl)transferase protein.
Still IH, Vince P, Cowell JK.
Genomics 1999 Dec; 62(3):533.
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The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase.
Kickhoefer VA, Siva AC, Kedersha NL, Inman EM, Ruland C, Streuli M, Rome LH.
The Journal of Cell Biology 1999 Sep; 146(5):917.
Application:IF, WB-Ce, Human, HeLa cells, Human foreskin fibroblasts.
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The DNA sequence and analysis of human chromosome 13.
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