KLK3 monoclonal antibody, clone A67-B/E3
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of KLK3 monoclonal antibody, clone A67-B/E3 (Cat # MAB0915) at 1 ug/ml with 1 mg/ml KLK3 (Human) Native Protein (Cat # P4872) purified from human seminal plasma.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry staining of human prostate (paraffin - embedded sections) with KLK3 monoclonal antibody, clone A67 - B/E3 (Cat # MAB0915) .
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Specification
Product Description
Mouse monoclonal antibody raised against native KLK3.
Immunogen
Native purified human KLK3.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein-A affinity chromatography.
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of KLK3 monoclonal antibody, clone A67-B/E3 (Cat # MAB0915) at 1 ug/ml with 1 mg/ml KLK3 (Human) Native Protein (Cat # P4872) purified from human seminal plasma.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry staining of human prostate (paraffin - embedded sections) with KLK3 monoclonal antibody, clone A67 - B/E3 (Cat # MAB0915) .Enzyme-linked Immunoabsorbent Assay
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Gene Info — KLK3
Entrez GeneID
354Gene Name
KLK3
Gene Alias
APS, KLK2A1, PSA, hK3
Gene Description
kallikrein-related peptidase 3
Omim ID
176820Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
P-30 antigen|gamma-seminoprotein|kallikrein 3, (prostate specific antigen)|prostate specific antigen|semenogelase|seminin
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Interactome
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Pathway
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Disease
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