CLCN6 monoclonal antibody (M05), clone 2H2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CLCN6.
Immunogen
CLCN6 (NP_001277.1, 770 a.a. ~ 868 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PRLSYAEMAEDYPRYPDIHDLDLTLLNPRMIVDVTPYMNPSPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGIITRHNLTYEFLQARLRQHYQT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CLCN6 is 1 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to CLCN6 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — CLCN6
Entrez GeneID
1185GeneBank Accession#
NM_001286Protein Accession#
NP_001277.1Gene Name
CLCN6
Gene Alias
CLC-6, KIAA0046
Gene Description
chloride channel 6
Omim ID
602726Gene Ontology
HyperlinkGene Summary
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This gene is in close vicinity to two other kidney-specific chloride channel genes, CLCNKA and CLCNKB. [provided by RefSeq
Other Designations
OTTHUMP00000002410|OTTHUMP00000042609|OTTHUMP00000042610|OTTHUMP00000042611|OTTHUMP00000042616|OTTHUMP00000042617
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Interactome
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Disease
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