CYP1B1 recombinant monoclonal antibody, clone R09-8C7
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human Cytochrome P450 1B1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human Cytochrome P450 1B1
Theoretical MW (kDa)
Calculated MW: 61 kD
Reactivity
Human
Form
Liquid
Isotype
IgG
Recommend Usage
Flow cytometry (1/50-1/100)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(1/50-1/100)
Western Blot (1/500-1/1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Flow Cytometry
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Gene Info — CYP1B1
Entrez GeneID
1545Gene Name
CYP1B1
Gene Alias
CP1B, GLC3A, P4501B1
Gene Description
cytochrome P450, family 1, subfamily B, polypeptide 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq
Other Designations
aryl hydrocarbon hydroxylase|cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile)|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase
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Interactome
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Pathway
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Disease
- Abortion
- Adenocarcinoma
- Adenoma
- Asperger Syndrome
- Asthma
- Atherosclerosis
- Autistic Disorder
- Brain Neoplasms
- Breast cancer
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