NR0B1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NR0B1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human NR0B1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Transfected lysate)
Western blot analysis of NROB1 (arrow) using rabbit NR0B1 polyclonal antibody (Cat # PAB2546). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NROB1 gene (Lane 2) (Origene Technologies). -
Gene Info — NR0B1
Entrez GeneID
190Protein Accession#
NP_000466;P51843Gene Name
NR0B1
Gene Alias
AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1
Gene Description
nuclear receptor subfamily 0, group B, member 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq
Other Designations
OTTHUMP00000023102|gonadotropin deficiency|nuclear hormone receptor
-
Interactome
-
Publication Reference
-
NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma.
Kinsey M, Smith R, Lessnick SL.
Molecular Cancer Research 2006 Nov; 4(11):851.
Application:WB-Tr, Human, TC71, EWS502, A673 cells.
-
NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com