CD44 monoclonal antibody (APC)
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Specification
Product Description
APC conjugated mouse CD44 monoclonal antibody.
Amenable Platform
Immunogen
Human recombinant CD44
Host
Mouse
Form
Liquid
Conjugation
APC
Concentration
0.5 mg/mL
Isotype
IgG2b, kappa
Available Test
16 assays
Quality Control Testing
Results
Sandwich ELISA
Sandwich ELISA performed with CD44 recombinant protein and CD44 monoclonal antibody (APC)
Immunofluorescence
Immunofluorescence staining performed on PC-3 cells using CD44 monoclonal antibody (APC) (10 ug/mL).
Recommend Usage
Immunofluorescence (10 ug/mL)
LiquidCell™ SuperSlide™ (6 uL per slide)Regulatory Status
Research Use Only
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at 2-8°C. Do not freeze.
Instrument Compatibility
Ventana™ BenchMark Stainer
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Applications
Immunofluorescence
Immunofluorescence staining performed on CTCs from the patient recoverd by SuperSlide™. CD44 was detected via red signal (APC). -
Gene Info — CD44
Entrez GeneID
960Gene Name
CD44
Gene Alias
CDW44, CSPG8, ECMR-III, HCELL, IN, LHR, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH-I, Pgp1
Gene Description
CD44 molecule (Indian blood group)
Omim ID
107269Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq
Other Designations
CD44 antigen|CD44 antigen (homing function and Indian blood group system)|CDW44 antigen|GP90 lymphocyte homing/adhesion receptor|Hermes antigen|antigen gp90 homing receptor|cell adhesion molecule|cell surface glycoprotein CD44|chondroitin sulfate proteogl
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Disease
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