KRAS Monoclonal antibody, clone (PAT2F8AT)
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Specification
Product Description
Mouse monoclonal antibody raised against human KRAS amino acids 1-186 purified from E. coli.
Immunogen
Anti-human KARS mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human KRAS amino acids 1-186 purified from E. coli.
Host
Mouse
Form
Liquid
Purification
Affinity chromatography
Recommend Usage
ELISA
Flow cytometry
Wester Blot
ICC/IF
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (10% glycerol and 0.02% NaN3)
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
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Gene Info — KRAS
Entrez GeneID
3845Protein Accession#
P01116Gene Name
KRAS
Gene Alias
C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2
Gene Description
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Gene Ontology
HyperlinkGene Summary
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq
Other Designations
K-ras p21 protein|Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog|PR310 c-K-ras oncogene|c-K-ras2 protein|c-Kirsten-ras protein|cellular c-Ki-ras2 proto-oncogene|oncogene KRAS2|transforming protein p21|v-Ki-ras2 Kirsten rat sarcoma 2 viral oncoge
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Interactome
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Pathway
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Disease
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