ADAM11 polyclonal antibody (A01)
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant ADAM11.
Immunogen
ADAM11 (NP_002381, 230 a.a. ~ 333 a.a) partial recombinant protein with GST tag.
Sequence
GHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVIYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHLFSGR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.55 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ADAM11
Entrez GeneID
4185GeneBank Accession#
NM_002390Protein Accession#
NP_002381Gene Name
ADAM11
Gene Alias
MDC
Gene Description
ADAM metallopeptidase domain 11
Omim ID
155120Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq
Other Designations
a disintegrin and metalloproteinase domain 11|metalloproteinase-like, disintegrin-like, cysteine-rich protein
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Interactomes
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Diseases
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