LIFR polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (38.21 KDa) .
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant LIFR.
Immunogen
LIFR (NP_002301, 45 a.a. ~ 154 a.a) partial recombinant protein with GST tag.
Sequence
QKKGAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (60); Rat (62)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — LIFR
Entrez GeneID
3977GeneBank Accession#
NM_002310Protein Accession#
NP_002301Gene Name
LIFR
Gene Alias
CD118, FLJ98106, FLJ99923, LIF-R, SJS2, STWS, SWS
Gene Description
leukemia inhibitory factor receptor alpha
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
CD118 antigen|leukemia inhibitory factor receptor
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Interactomes
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Pathways
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