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Fluorescence In Situ Hybridization (FISH)

FISH is a technique used to identify and localize the presence or absence of specific DNA sequences on cells and tissues. Abnova has developed a range of FISH probes for the detection of gene amplification, loss and translocation. Each FISH probe product has a pair of locus-specific, fluorophore-labeled probes originated from a bacterial artificial chromosome (BAC) library. We continue to expand the scope of the FISH probes to meet the customer’s research needs. Custom probes are also available upon request.


  • Dual colored probes for fast, sensitive, and specific detection
  • Work on metaphase spread, paraffin embedded and frozen tissue
  • Identify gene amplification, loss, and translocation
  • High signal to noise ratio
  • Low cross reactivity
Product Lines

        Gene Amplification / Gene Loss
        Split Dual Color FISH Probe
        Translocation Dual Color FISH Probe

Publication Reference

DNA sequence and analysis of human chromosome 8
Nusbaum C, Mikkelsen TS, Zody MC, Asakawa S, and et al. Nature. 2006 Jan 19;439(7074):331-5.
Initial sequencing and analysis of the human genome
Lander ES, Linton LM, Birren B, Nusbaum C, and et al. Nature. 2001 Feb 15;409(6822):860-921.
A physical map of the human genome.
McPherson JD, Marra M, Hillier L, Waterston RH, and et al. Nature. 2001 Feb 15;409(6822):934-41.
Human BAC library: construction and rapid screening.
Asakawa S, Abe I, Kudoh Y, Kishi N, Wang Y, Kubota R, Kudoh J, Kawasaki K, Minoshima S, Shimizu N. Gene. 1997 May 20;191(1):69-79.
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