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Last updated: 2023/3/26

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CD40 Humanized monoclonal antibody, clone 6EOG 

  • Catalog # : RAB01126-M01J
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  • Specification
  • Product Description:
  • Humanized monoclonal antibody raised against CD40.
  • Immunogen:
  • Recombinant protein corresponding to Human CD40.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Isotype:
  • Human IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of RAB01126-M01J
    Western Blot detection against Immunogen.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometry analysis of human CRC CD3 T cells were treated with CD40 Humanized monoclonal antibody, clone 6EOG (Cat # RAB01124-M01J). This antibody efficiently bound to human CD3 T cells.
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • CD40 Humanized monoclonal antibody, clone 6EOG. Western Blot analysis of CD40 expression in B-LCL.
  • PDF DownloadProtocol Download
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 958
  • Gene Name:
  • CD40
  • Gene Alias:
  • Bp50,CDW40,MGC9013,TNFRSF5,p50
  • Gene Description:
  • CD40 molecule, TNF receptor superfamily member 5
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • B cell surface antigen CD40,B cell-associated molecule,CD40 antigen,CD40 antigen (TNF receptor superfamily member 5),CD40 type II isoform,CD40L receptor,OTTHUMP00000031699,OTTHUMP00000031700,nerve growth factor receptor-related B-lymphocyte activation mol
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