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Last updated: 2023/3/26

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4-1BB Humanized monoclonal antibody, clone D2D 

  • Catalog # : RAB01123-M01J
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  • Specification
  • Product Description:
  • Humanized monoclonal antibody raised against 4-1BB.
  • Immunogen:
  • Recombinant protein corresponding to Human 4-1BB.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Isotype:
  • Human IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of RAB01123-M01J
    Western Blot detection against Immunogen.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometry analysis of human CRC CD3 T cells were treated with 4-1BB Humanized monoclonal antibody, clone D2D (Cat # RAB01123-M01J). This antibody efficiently bound to human CD3 T cells.
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • 4-1BB Humanized monoclonal antibody, clone D2D. Western Blot analysis of 4-1BB expression in Jurkat.
  • PDF DownloadProtocol Download
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3604
  • Gene Name:
  • TNFRSF9
  • Gene Alias:
  • 4-1BB,CD137,CDw137,ILA,MGC2172
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 9
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq
  • Other Designations:
  • 4-1BB ligand receptor,CD137 antigen,OTTHUMP00000001360,OTTHUMP00000044294,T cell antigen ILA,homolog of mouse 4-1BB,induced by lymphocyte activation (ILA),interleukin-activated receptor, homolog of mouse Ly63,receptor protein 4-1BB
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