CREB1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
CREB1 polyclonal antibody (Cat # PAB9994) is shown to detect CREB1 present in Raji B cell nuclear extract.
Detection occurs using a 1 : 1,000 dilution of antibody followed by a 1 : 5,000 dilution of HRP Goat-a-Rabbit IgG with visualization via ECL.
Film exposure was approximately 1'.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CREB1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus human CREB1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Anti-CREB-1 (p43) may react non-specifically with other proteins. A partial cross-reactivity is observed against CREM-1 protein.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:500-1:1000)
Gel Supershift Assay (0.5-1.0 ul per assay)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
CREB1 polyclonal antibody (Cat # PAB9994) is shown to detect CREB1 present in Raji B cell nuclear extract.
Detection occurs using a 1 : 1,000 dilution of antibody followed by a 1 : 5,000 dilution of HRP Goat-a-Rabbit IgG with visualization via ECL.
Film exposure was approximately 1'.Enzyme-linked Immunoabsorbent Assay
Gel Supershift Assay
-
Gene Info — CREB1
Entrez GeneID
1385Gene Name
CREB1
Gene Alias
CREB, MGC9284
Gene Description
cAMP responsive element binding protein 1
Omim ID
123810Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
active transcription factor CREB|cAMP-response element-binding protein-1|transactivator protein
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
CREB regulates MHC class II expression in a CIITA-dependent manner.
Moreno CS, Beresford GW, Louis-Plence P, Morris AC, Boss JM.
Immunity 1999 Feb; 10(2):143.
Application：WB-Re, Recombinant protein.
-
CREB regulates MHC class II expression in a CIITA-dependent manner.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com