GFAP polyclonal antibody (Cat # PAB7137) (0.01 ug/mL) staining of Human Cerebellum (1), Mouse Brain (2) and (0.003 ug/mL) Rat Brain (3) lysate (35 ug protein in RIPA buffer). Detected by chemiluminescence.
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq