P2RY12 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry
Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in microglia.
Immunohistochemistry
Immunohistochemical staining of human cerebellum shows strong cytoplamic positivity in microglia.
Immunohistochemistry
Immunohistochemical staining of human liver shows no positivity as expected.
Immunohistochemistry
Immunohistochemical staining of human testis shows no positivity in cells in semiferous ducts as expected.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human P2RY12.
Sequence
KSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts to P2RY12.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:1000 - 1:2500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in microglia.Immunohistochemistry
Immunohistochemical staining of human cerebellum shows strong cytoplamic positivity in microglia.Immunohistochemistry
Immunohistochemical staining of human liver shows no positivity as expected.Immunohistochemistry
Immunohistochemical staining of human testis shows no positivity in cells in semiferous ducts as expected. -
Gene Info — P2RY12
Entrez GeneID
64805Gene Name
P2RY12
Gene Alias
ADPG-R, HORK3, P2T(AC), P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999
Gene Description
purinergic receptor P2Y, G-protein coupled, 12
Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq
Other Designations
ADP-glucose receptor|G-protein coupled receptor SP1999|Gi-coupled ADP receptor HORK3|P2Y purinoceptor 12|platelet ADP receptor|purinergic receptor P2RY12|purinergic receptor P2Y12|putative G-protein coupled receptor
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Interactome
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Disease
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