APP fibrils polyclonal antibody (FITC)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Application Data with Unconjugated Antibody
Western Blot
Western blot analysis of Abeta42 fibrils (Lane 1, Lane 3) and prefibrillar oligomers (Lane 2, Lane 4) with APP fibrils polyclonal antibody(Cat # PAB28910; Lane 1, Lane 2) and APP oligomers polyclonal antibody (Cat # PAB28928; Lane 3, Lane 4).
Application Data with Unconjugated Antibody
Dot Blot
Dot blot analysis of Abeta42 and polyQ36 prefibrillar oligomers and fibrils with APP oligomers polyclonal antibody (Cat # PAB28928) and APP fibrils polyclonal antibody (Cat # PAB28910).
-
Specification
Product Description
Rabbit polyclonal antibody against amyloid fibrils and fibrillar oligomers.
Immunogen
Fibrils prepared from human Abeta42 peptide.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
PAB28922 recognizes generic epitopes common to many amyloid fibrils and fibrillar oligomers, but not prefibrilllar oligomers or natively folded proteins. 1:1000 dilution of PAB28922 was sufficient for detection of amyloid oligomers in 10ug of mouse brain lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Form
Liquid
Conjugation
FITC
Purification
Protein A affinity purification
Recommend Usage
Dot blot (1:1000)
ELISA
Immunocytochemistry
Immunohistochemistry
Immunoprecipitation
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
PBS pH7.4, 50% glycerol and 0.09% sodium azide
Storage Instruction
Store at 4°C.
Aliquot to avoid repeated freezing and thawing.Note
Application Data with Unconjugated Antibody
Western Blot
Western blot analysis of Abeta42 fibrils (Lane 1, Lane 3) and prefibrillar oligomers (Lane 2, Lane 4) with APP fibrils polyclonal antibody(Cat # PAB28910; Lane 1, Lane 2) and APP oligomers polyclonal antibody (Cat # PAB28928; Lane 3, Lane 4).
Dot Blot
Dot blot analysis of Abeta42 and polyQ36 prefibrillar oligomers and fibrils with APP oligomers polyclonal antibody (Cat # PAB28928) and APP fibrils polyclonal antibody (Cat # PAB28910).
-
Applications
Western Blot
Immunohistochemistry
Immunocytochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
Dot Blot
-
Gene Info — APP
Entrez GeneID
351Protein Accession#
P05067Gene Name
APP
Gene Alias
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2
Gene Description
amyloid beta (A4) precursor protein
Gene Ontology
HyperlinkGene Summary
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
A4 amyloid protein|amyloid beta A4 protein|amyloid-beta protein|beta-amyloid peptide|cerebral vascular amyloid peptide|peptidase nexin-II|protease nexin-II
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com