SERPINC1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bone marrow with SERPINC1 polyclonal antibody (Cat # PAB28488) shows strong cytoplasmic positivity in bone marrow poietic cells at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SERPINC1.
Immunogen
Recombinant protein corresponding to amino acids of human SERPINC1
Sequence
HGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry(1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bone marrow with SERPINC1 polyclonal antibody (Cat # PAB28488) shows strong cytoplasmic positivity in bone marrow poietic cells at 1:50-1:200 dilution. -
Gene Info — SERPINC1
Entrez GeneID
462Protein Accession#
P01008Gene Name
SERPINC1
Gene Alias
AT3, ATIII, MGC22579
Gene Description
serpin peptidase inhibitor, clade C (antithrombin), member 1
Omim ID
107300Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq
Other Designations
OTTHUMP00000035393|antithrombin (aa 375-432)|antithrombin III|coding sequence signal peptide antithrombin part 1|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1|signal peptide antithrombin part 1
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Interactome
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Pathway
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Disease
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