TOP3B polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with TOP3B polyclonal antibody (Cat # PAB27152).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TOP3B.
Immunogen
A synthetic peptide corresponding to human TOP3B.
Host
Rabbit
Theoretical MW (kDa)
96
Reactivity
Human, Mouse
Specificity
TOP3B polyclonal antibody detects endogenous levels of TOP3B protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with TOP3B polyclonal antibody (Cat # PAB27152).Immunohistochemistry
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Gene Info — TOP3B
Entrez GeneID
8940Protein Accession#
O95985Gene Name
TOP3B
Gene Alias
FLJ39376
Gene Description
topoisomerase (DNA) III beta
Omim ID
603582Gene Ontology
HyperlinkGene Summary
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described. [provided by RefSeq
Other Designations
topoisomerase III beta
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Interactome
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Pathway
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