SSB polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with SSB polyclonal antibody (Cat # PAB24863).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SSB polyclonal antibody (Cat # PAB24863).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SSB.
Immunogen
A synthetic peptide corresponding to SSB.
Host
Rabbit
Theoretical MW (kDa)
~50.0
Reactivity
Human
Specificity
SSB polyclonal antibody detects endogenous levels of SSB protein.
Form
Liquid
Purification
Antigen affinity purification
Purity
> 95% by SDS-PAGE
Recommend Usage
Western Blot (1:500-1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1x PBS, pH 7.2 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with SSB polyclonal antibody (Cat # PAB24863).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SSB polyclonal antibody (Cat # PAB24863). -
Gene Info — SSB
Entrez GeneID
6741Gene Name
SSB
Gene Alias
LARP3, La
Gene Description
Sjogren syndrome antigen B (autoantigen La)
Omim ID
109090Gene Ontology
HyperlinkGene Summary
La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006 [PubMed 16387655]).[supplied by OMIM
Other Designations
La ribonucleoprotein domain family, member 3|SS-B/La protein|autoantigen La
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Interactome
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Pathway
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Disease
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