CLDN1 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of HEK293 cells over-expressing SLC2A1 (Lane 1) or a nono-specific control receptor (Lane 2) using CLDN1 polyclonal antibody (Cat # PAB19765) at 1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinant CLDN1.
Immunogen
Recombinant protein corresponding to full length human CLDN1.
Sequence
MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
Host
Rabbit
Theoretical MW (kDa)
22.7
Reactivity
Human
Specificity
It displayed on membrane surface of lipoparticles.
Form
Liquid
Recommend Usage
Western Blot (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In unpurified whole serum
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Transfected lysate)
Western blot analysis of HEK293 cells over-expressing SLC2A1 (Lane 1) or a nono-specific control receptor (Lane 2) using CLDN1 polyclonal antibody (Cat # PAB19765) at 1:200 dilution. -
Gene Info — CLDN1
Entrez GeneID
9076GeneBank Accession#
NM_021101Protein Accession#
NP_066924Gene Name
CLDN1
Gene Alias
CLD1, ILVASC, SEMP1
Gene Description
claudin 1
Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq
Other Designations
senescence-associated epithelial membrane protein 1
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Interactome
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Pathway
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Disease
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