App polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of App.
Immunogen
A synthetic peptide (conjugated with blue carrier protein) corresponding to amino acids 44-62 of mouse App.
Sequence
HMNVQNGKWESDPSGTKTC
Host
Rabbit
Reactivity
Mouse, Rat
Form
Lyophilized
Recommend Usage
Immunohistochemistry (1:500-1:3000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from whole serum
Storage Instruction
After reconstitution with deionized water (100 uL sterile-filtered), store at -20°C for a higher stability, or at 4°C with an appropriate antibacterial agent.
Glycerol (1:1) may be added for an additional stability.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Frozen sections)
Immunohistochemical staining on rat dorsal root ganglion (free floating cryo section) using App polyclonal antibody (Cat # PAB14316) at a dilution of 1 : 1000. -
Gene Info — App
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Publication Reference
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Mechanisms of Abeta clearance and catabolism.
Guenette SY.
Neuromolecular Medicine 2003 Dec; 4(3):147.
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Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular Abeta production.
Wilson CA, Doms RW, Lee VM.
Journal of Neuroscience 2003 Nov; 74(3):361.
Application:WB, Human, Mammalian cells.
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CSF markers for Alzheimer's disease: total tau, phospho-tau and Abeta42.
Andreasen N, Sjogren M, Blennow K.
The World Journal of Biological Psychiatry 2003 Oct; 4(4):147.
Application:ELISA, Human, Human cerebrospinal fluid.
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Mechanisms of Abeta clearance and catabolism.
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