COMP polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against native COMP.
Immunogen
Native purified human COMP.
Host
Rabbit
Reactivity
Bovine, Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1:200-1:500)
Immunohistochemistry (Frozen sections) (1:50-1:100)
Immunoprecipitation (1:10-1:50)
The optimal working dilution should be determined by the end user.Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Frozen sections)
Immunoprecipitation
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Gene Info — COMP
Entrez GeneID
1311Gene Name
COMP
Gene Alias
EDM1, EPD1, MED, MGC131819, MGC149768, PSACH, THBS5
Gene Description
cartilage oligomeric matrix protein
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq
Other Designations
cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple)|cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple)|pseudoachondroplasia (epiphyseal dysplasia 1, multiple)|thrombospondin
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Interactome
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Pathway
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Disease
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