BST2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BST2.
Immunogen
A synthetic peptide corresponding to C-terminus 16 amino acids of human BST2.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of BST2 in Daudi cell lysate with BST2 polyclonal antibody (Cat # PAB13047) at (A) 1 and (B) 2 ug/mL . -
Gene Info — BST2
Entrez GeneID
684Protein Accession#
AAH87949Gene Name
BST2
Gene Alias
CD317
Gene Description
bone marrow stromal cell antigen 2
Omim ID
600534Gene Ontology
HyperlinkGene Summary
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq
Other Designations
tetherin
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Interactome
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Disease
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Publication Reference
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A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo.
Barrett BS, Smith DS, Li SX, Guo K, Hasenkrug KJ, Santiago ML.
PLoS Pathogens 2012 Mar; 8(3):e1002596.
Application:Flow Cyt, Mouse, Splenocytes.
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Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu.
Neil SJ, Zang T, Bieniasz PD.
Nature 2008 Jan; 451(7177):425.
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Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.
Ishikawa J, Kaisho T, Tomizawa H, Lee BO, Kobune Y, Inazawa J, Oritani K, Itoh M, Ochi T, Ishihara K, et al..
Genomics 1995 Apr; 26(3):527.
Application:Flow Cyt, IP, Human, HEK 293T cells, MMSV3-3, NFSV1-1, NIH/3T3, RASV55, SynSV6-14 cells.
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A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo.
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