TLR2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TLR2.
Immunogen
A mixture of synthetic peptides corresponding to amino acids 180-196, 353-370 and 473-489 of human TLR2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of TLR2 in transfected THP-1 cell lysate using TLR2 polyclonal antibody (Cat # PAB0195) at 2 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of TLR2 in paraffin-embedded formalin-fixed mouse pancreas tissue using an isotype control (top) and TLR2 polyclonal antibody (Cat # PAB0195) (bottom) at 5 ug/mL . -
Gene Info — TLR2
Entrez GeneID
7097Gene Name
TLR2
Gene Alias
CD282, TIL4
Gene Description
toll-like receptor 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq
Other Designations
toll/interleukin 1 receptor-like 4
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Interactome
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Pathway
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Disease
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