RUNX1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of RUNX1 in (A) human Ramos and (B) mouse Raw cell lysate using RUNX1 polyclonal antibody (Cat # PAB0189) at 5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RUNX1.
Immunogen
A synthetic peptide corresponding to amino acids 231-245 of human RUNX1.
Sequence
AFNPQPQSQMQDTRQ
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of RUNX1 in (A) human Ramos and (B) mouse Raw cell lysate using RUNX1 polyclonal antibody (Cat # PAB0189) at 5 ug/mL . -
Gene Info — RUNX1
Entrez GeneID
861Gene Name
RUNX1
Gene Alias
AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2aB
Gene Description
runt-related transcription factor 1
Gene Ontology
HyperlinkGene Summary
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
AML1-EVI-1 fusion protein|acute myeloid leukemia 1|aml1 oncogene|core-binding factor, runt domain, alpha subunit 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Physiogenomic resources for rat models of heart, lung and blood disorders.
Malek RL, Wang HY, Kwitek AE, Greene AS, Bhagabati N, Borchardt G, Cahill L, Currier T, Frank B, Fu X, Hasinoff M, Howe E, Letwin N, Luu TV, Saeed A, Sajadi H, Salzberg SL, Sultana R, Thiagarajan M, Tsai J, Veratti K, White J, Quackenbush J, Jacob HJ, Lee NH.
Nature Genetics 2006 Jan; 38(2):234.
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Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
Srivastava MD, Srivastava BI.
Leukemia Research 2005 Jul; 29(7):813.
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Physiogenomic resources for rat models of heart, lung and blood disorders.
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