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Last updated: 2023/3/26

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FGF8 (Human) Recombinant Protein 

  • Catalog # : P8603
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  • Specification
  • Product Description:
  • Human FGF8 recombinant protein expressed in?Escherichia coli.
  • Sequence:
  • MQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 22.5
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • > 95% as determined by SDS-PAGE.
  • Activity:
  • ED50 is 0.915 ng/mL, measure by its ability to induce proliferation of NR6-R 3T3, corresponding to a Specific Activity of 1.1 x 106Units/mg.
  • Storage Buffer:
  • Lyophilized from a solution containing 0.1% TFA. Reconstitute the lyophilized powder in ddH2O to 100 ug/mL.
  • Storage Instruction:
  • Lyophilized protein at room temperature for 3 weeks, should be stored at -20°C. Protein aliquots at 4°C for 2-7 days and should be stored at -20°C to -80°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Avoid repeated freeze/thaw cycles.
  • Applications
  • Functional Study
  • Application Image
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 2253
  • Gene Name:
  • FGF8
  • Gene Alias:
  • AIGF,HBGF-8,MGC149376
  • Gene Description:
  • fibroblast growth factor 8 (androgen-induced)
  • Gene Summary:
  • The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020348,OTTHUMP00000020349,OTTHUMP00000020350,OTTHUMP00000020351,androgen-induced growth factor,fibroblast growth factor 8
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