Product Browser

Last updated: 2023/3/26

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location
Bulk order
Custom Services
2019 Next Day Shipping

IGFBP3 (Human) Recombinant Protein 

  • Catalog # : P8192
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Human IGFBP3 (P17936, 28 a.a. - 291 a.a.) partial recombinant protein expressed in Escherichia coli.
  • Sequence:
  • GASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 28.8
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • > 97% by SDS-PAGE
  • Activity:
  • The ED50 is < 200ng/mL, calculated by by its ability to inhibit IGF-II induced proliferation of MCF-7 in the presence of 15ng/mL of Human IGF-II, corresponding to a specific activity of 5.0 × 103 IU/mg.
  • Recommend Usage:
  • Biological Activity
    SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In sterile 20mM AcOH (acetic Acid) > 100 ug/mL
  • Storage Instruction:
  • Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3486
  • Gene Name:
  • IGFBP3
  • Gene Alias:
  • BP-53,IBP3
  • Gene Description:
  • insulin-like growth factor binding protein 3
  • Gene Summary:
  • This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • IGF-binding protein 3,acid stable subunit of the 140 K IGF complex,binding protein 29,binding protein 53,growth hormone-dependent binding protein
  • Gene Pathway
  • Related Disease
  • RSS
  • YouTube
  • Linkedin
  • Facebook