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Last updated: 2023/3/26

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INS (Human) Recombinant Protein BioActive

  • Catalog # : P8131
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  • Specification
  • Product Description:
  • Human INS (P01308) recombinant protein expressed in Escherichia coli .
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 5.8
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • > 98% by RP-HPLC analysis
  • Activity:
  • The Biological Activity was determined to be 28 units/mg.
  • Storage Buffer:
  • Lyophilized from with no additives
  • Storage Instruction:
  • Lyophilized although stable at room temperature for 3 weeks, should be stored desiccated below -20°C. Upon reconstitution should be stored at 4°C between 2-7 days and for future use below -20°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3630
  • Gene Name:
  • INS
  • Gene Alias:
  • ILPR,IRDN
  • Gene Description:
  • insulin
  • Gene Summary:
  • After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000011161,OTTHUMP00000011162,OTTHUMP00000196038,proinsulin
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